A number of reviews have stated that tetracycline is contraindicated during breastfeeding because of possible staining of infants' dental enamel or bone deposition of tetracyclines. No gross adverse effect occurred in any of the breastfed infants. Antibiot Annu. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of tetracycline during lactation because milk levels are low and absorption by the infant is inhibited by the calcium in breastmilk. See references. 25. Milk calcium may inhibit absorption of the small amounts of tetracyclines in milk.Relevant published information was not found as of the revision date.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Gavreto (pralsetinib) is an oral selective RET kinase inhibitor for the...Onureg (azacitidine) is a nucleoside metabolic inhibitor indicated for the...Qdolo (tramadol hydrochloride) is an opioid agonist indicated in adults for ...Xaracoll (bupivacaine hydrochloride) is a fully bioresorbable collagen implant...The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Tetracyclines have been considered contraindicated during breastfeeding due to possible staining of infants' dental enamel or bone deposition of tetracyclines; however, a close review of available literature suggests harmful effects are unlikely with short-term use of this drug during lactation as milk levels are low and infant absorption is inhibited by the calcium in breast milk. Select one or more newsletters to continue. As a theoretical precaution, avoid prolonged or repeat courses during nursing. The fetal and newborn liver cannot metabolize the drug and anemia results.
Tetracyclines used during tooth development in the last half of pregnancy and in infancy can cause a permanent yellow-gray discoloration of the teeth and make the tooth enamel thinner. Further observations on the use of tetracycline hydrochloride in prophylaxis and treatment of obstetric infections. Ages of the infants and extent of breastfeeding were not stated. Emtet-500, Tetracon, Sumycin 250, Sumycin, TopicyclineWe comply with the HONcode standard for trustworthy health information - Theoretical risks of dental staining and inhibition of bone growth exist, although are unlikely. In an observational study of 251 women, 23.8% of nursing mothers received tetracycline during breastfeeding. Tetracycline is considered compatible with breast-feeding by the American Academy of Pediatrics. Milk levels ranged from 0.43 to 2.58 mg/L (times not specified). Drug exposure in pregnant and lactating mothers in periurban areas. 1984;5:57-60. 1955;15:354-60. No adverse effects were noted in an unspecified number of breastfed infants whose mothers were taking oral tetracycline 1, 1.5 or 2 grams daily for 3 days. However, the manufacturer recommends that because of the risk of serious potential adverse reactions in nursing infants, a decision should be made whether to continue breast-feeding or discontinue the drug, taking into account the importance of the drug to the mother.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In one study, tetracycline levels were undetectable in nursing infants. Select one or more newsletters to continue. Tetracycline is excreted into human milk in small amounts. It should be avoided during pregnancy unless the risk of a blood clot is more dangerous than the risk of harm to the baby. Indian Pediatr. [The excretion of terramycin and tetracycline in human milk]. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).Five women were given oral tetracycline 500 mg 4 times a day for 3 days. Geburtshilfe Frauenheilkd. [PubMed The use of tetracycline during pregnancy is generally not recommended, especially during the last half of pregnancy. 1990;27:1301-2. Theoretical risks of dental staining and inhibition of bone growth exist, although are unlikely. In one study, tetracycline levels were undetectable in nursing infants. Why should tetracycline drugs be avoided during pregnancy and lactation?
c. The fetus and newborn are more likely to … a. Tetracycline crosses the placenta and causes brain hemorrhage in the fetus. Available for Android and iOS devices. Biol Res Pregnancy. There are no controlled data in human pregnancy, however, congenital defects and maternal hepatotoxicity have been reported. Although it is often stated that tetracyclines are to be avoided during lactation because of tooth staining, this adverse effect has never been reported after exposure via breastmilk.