Copyright © 2019 Elsevier Ltd. All rights reserved. Deficiency is strongly linked to increased risk for a multitude of diseases, several of which have historically been shown to improve dramatically with either adequate UVB exposure to the skin, or to oral or topical supplementation with vitamin D. These diseases include asthma, psoriasis, rheumatoid arthritis, rickets and tuberculosis. In summary, long-term supplementation with vitamin D3 in doses ranging from … There have been no cases of vitamin D3 induced hypercalcemia or any adverse events attributable to vitamin D3 supplementation in any patient.
Three patients with psoriasis showed marked clinical improvement in their skin using 20,000 to 50,000 IUs/day. Vitamin D3 dosage for adults, in particular, can be much higher than the 200 IU of D3 daily recommended for adults under the age of 50 and the 400 IU of D3 daily recommended for adults 50 and older. The average serum calcium level in these 2 groups was 9.5 (no D3) vs 9.6 (D3), with ranges of 8.4 to 10.7 (no D3) vs 8.6 to 10.7 mg/dl (D3), after excluding patients with other causes of hypercalcemia. The average intact parathyroid hormone levels were 24.2 pg/ml (D3) vs. 30.2 pg/ml (no D3). One study found that 1 in 3 professional surfers on the north shore of Maui, where the sun shines nearly every day, had a vitamin D3 deficiency.Since toxicity symptoms are unknown below daily dosages of 40,000 IU per day, the US Institute of Medicine recommends taking up to 4,000 IU per day as an unquestionably safe dosage. Analysis of 777 recently tested patients (new and long-term) not on D3 revealed 28.7% with 25-hydroxyvitaminD3 (25OHD3) blood levels < 20 ng/ml, 64.1% < 30 ng/ml, a mean 25OHD3 level of 27.1 ng/ml, with a range from 4.9 to 74.8 ng/ml.
2015 Aug 4;16:128. doi: 10.1186/s12882-015-0116-3.Bjelakovic G, Gluud LL, Nikolova D, Whitfield K, Wetterslev J, Simonetti RG, Bjelakovic M, Gluud C.Cochrane Database Syst Rev. 2010 Sep 1;202(5):809-14.HealthifyBody.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com, as well as other affiliate companies.Robert Rister is the author of Healing without Medication and many other books that have been translated into eight languages. Serum 25OHD, calcemia and calciuria were measured just before the first dose (Month 0), just before the 4th dose (M4), and one month after the 6th dose (M7). Online ahead of print.Front Neurol. doi: 10.1186/cc10120. In the 1930's, vitamin D3 was the recognized as a nearly miraculous tool for preventing the then-common childhood disease known as rickets.Children who had to go to work at an early age in poorly lit factories, and who lived in cities where the sky was permanently dark with coal ash, developed weak and wobbly bones. Taking a supplement of up to 1,000 IU of vitamin D a day acts as "insurance" that your tissues will always have the activated vitamin D they need.How much vitamin D3 should I take if I am deficient? The average intact parathyroid hormone levels were 24.2 pg/ml (D3) vs. 30.2 pg/ml (no D3). 2020 Apr 2;12(4):988. doi: 10.3390/nu12040988.
For people with a severe vitamin D deficiency confirmed in blood tests, some health care providers are prescribing a mega-dose: 50,000 IU vitamin D taken once a week for six to eight weeks. Part of the reason for this is that your parathyroid glands are usually less efficient at converting the storage form of vitamin D, D3, into the active form of vitamin D, D2.Keeping enough vitamin D2 in your bloodstream requires having more D3 stored in skin and fat.
Dosage depends on your age and general health, but around 1000-4000 IU daily (or 2000 IU daily on average) is sufficient to ensure optimal blood levels in most people. 2020 May 29:S0214-9168(20)30048-6. doi: 10.1016/j.arteri.2020.05.003. Elsevier Science