Hydroxyurea is used in adult patients with sickle cell anemia to prevent painful episodes and reduce the need for blood transfusions. Hydroxyurea is associated with a low rate of transient serum enzyme and bilirubin elevations during therapy, and has been implicated in rare cases of clinically apparent acute liver injury with jaundice. Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Hydroxyurea is used to treat cancer of the white blood cells called chronic myeloid leukemia (CML).

and a collection of links to more information about the use of Hydroxyurea is an antimetabolite that is used in the treatment of cancer and to stimulate fetal hemoglobin production in sickle cell disease. It may also be given together with radiation treatment for head and neck cancer (advanced squamous cell cancer). ; The use of hydroxyurea to treat cancer is approved for the Hydrea brand. Hydroxyurea The brand of hydroxyurea capsules called Hydrea® is prescribed for people with some types of cancer, and also for people with a condition known as polycythemia rubra vera. This medicine is available only with your doctor's prescription. Hydroxyurea is also used to reduce pain episodes and the need for blood transfusions in people with sickle cell anemia. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. So, raising the fetal haemoglobin level in people with SCD can reduce the effects of the disease. Hydroxyurea will not cure sickle cell anemia. This patient information sheet applies only to approved uses of the drug. The drug hydroxyurea is used to raise fetal haemoglobin. Many children with sickle cell disease have taken hydroxyurea for several years without problems. This product is available in the following dosage forms:Portions of this document last updated: Feb. 01, 2020Copyright © 2020 IBM Watson Health. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Hydroxyurea is very safe when given by medical specialists experienced in caring for patients with sickle cell disease. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products.

J Urol 1998; 159:1642. Hydroxyurea is used to treat chronic myeloid leukemia, ovarian cancer, and certain types of skin cancer (squamous cell cancer of the head and neck). The brands of hydroxyurea capsules called Droxia® and Siklos® are prescribed for people with sickle cell disease. We looked for studies which compared hydroxyurea to placebo for longer than one month. However, much of the information may also apply to unapproved uses that are being studied. Hydroxyurea is used in adult patients with sickle cell anemia to prevent painful episodes and reduce the need for blood transfusions. Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism.
Results show a WBC = 6.2 x 10³ cells/mm³, neutrophils 32%, bands 9%, lymphocytes 45%, eosinophils 5%, basophils 1%, monocytes 8%. Hydroxyurea in the treatment of sickle cell associated priapism. All rights reserved. Hydroxyurea is approved to treat: Chronic myelogenous leukemia that is refractory (does not respond to treatment). is also being studied in the treatment of other Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for.

Hydroxyurea interferes with the growth of cancer cells, which are eventually destroyed by the body. ; Squamous cell carcinoma of the head and neck (excluding the lip) that is locally advanced.It is used with chemoradiation. This product is available in the following dosage forms: Tablet; Capsule; Before Using This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Use in Cancer. This medicine is available only with your doctor's prescription. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. A patient taking hydroxyurea for sickle cell disease follows up in clinic to have a CBC with differential checked. FDA label information for this drug is available at DailyMed. It works by making the red blood cells more flexible.
Fetal haemoglobin stops crystals forming in the sickle haemoglobin within the red blood cell. weakness, or loss of appetite. In children with sickle cell disease it takes several months to reach the full dose of hydroxyurea.