Metformin may also result in malabsorption of vitamin B12 in your small intestine. The main focus of treating PCOS is to manage symptoms such as hirsutism, infertility, obesity, … Metformin used for PCOS: The Science PCOS is an infertility condition that often causes acne, facial hair growth, balding, low sex drive, weight gain, difficulty with weight loss, and mental health disturbances such as depression and anxiety in approximately 15% of women. Metformin has been studied in girls as young as 8 years of age, with some researchers recommending it to prevent the onset of PCOS.Metformin lowers blood glucose and insulin levels in three ways: The use of metformin may prove beneficial in a subset of the population of women with PCOS. Some of these symptoms are nausea, flatulence, diarrhea, bloating, metallic taste, abdominal pain, and anorexia.
The main adverse effects that may occur while taking metformin for PCOS include various gastrointestinal symptoms.The severity of the side effects varies from patient to patient, but in the majority of cases, symptoms get better on their own. Diet and Lifestyle Changes Trump Metformin for PCOS. Given the important role insulin resistance plays in the pathophysiology of PCOS, common treatments involve insulin and the diabetic drug metformin, which improves insulin sensitivity. To learn what we do to deliver the best health and lifestyle insights to you, check out Polycystic ovary syndrome (PCOS) remains one of the most common disorders of the endocrine system, affecting between 4 and 12 percent of women worldwide. Angela Grassi, MS, RDN, LDN, is the founder of the PCOS Nutrition Center.
Overall, most people can tolerate metformin just fine. It also helps in losing weight and slowing the progression of prediabetes to type 2 diabetes. Elevated serum homocysteine and urinary methylmalonic acid (MMA) levels, the gold standard in assessing B12, also indicate a B12 deficiency.
The most serious side effect of metformin is lactic acidosis, a condition caused by the buildup of lactic acid in the blood. Health Insights
Weight loss may help in reducing the levels of androgens and insulin and in restoring ovulation. The use of metformin for PCOS is contraindicated if you have any of the following conditions: Kidney dysfunction; Hypersensitivity to the drug (metformin) Congestive heart failure; Impaired liver function; Chronic or acute metabolic acidosis; Metformin alternatives: other ways to treat PCOS. There are specific diets recommended for people with PCOS. Metformin for PCOS: Health Benefits, Risks, and Alternatives Personalize Your Flo
This can occur if too much metformin accumulates in the blood due to chronic or acute kidney problems.
Nausea and gastrointestinal issues such as stomach pain, gas, bloating, and diarrhea are some of the most common side effects. A diet rich in carbohydrates and low in fat may increase your insulin levels.
Although usually used to treat type 2 diabetes, metformin can also help relieve insulin resistance in women with PCOS. N-acetyl cysteine is an antioxidant that was shown in one randomized controlled trial to work as well as metformin for reducing insulin and cholesterol in women with PCOS.